Dr. George Muschler

Dr. George Muschler

Professor of Orthopaedic Surgery & Biomedical Engineering | Cleveland Clinic

    Dr. George Muschler is a Professor of Orthopaedic Surgery and Biomedical Engineering at the Cleveland Clinic, with a clinical practice that integrates joint replacement and joint preservation.

    Muschler’s Regenerative Medicine Laboratory has earned continuous federal funding for more than 28 years, focusing on stem and progenitor cell biology, tissue engineering and regenerative medicine. His current work is focused on understanding and managing clonal heterogeneity and quality in generation of MSC and iPSC populations using quantitative image analysis and precision automation.

    He has served as Vice Chair of Bioengineering (2004-2013); Director of the Orthopaedic Research Center (2005-2013), Vice Chair of the Orthopaedic and Rheumatologic Institute (2007-2013) and has served as Director of the Cleveland Clinic Joint Preservation Center since 2017.

    Muschler led the development of several multi-institutional collaborative translational networks. He founded and led the Ohio-based Clinical Tissue Engineering Center (2005-2012), and served as the founding Co-Director of the Armed Forces Institute of Regenerative Medicine (AFIRM) (2008-2011), dedicated to the accelerated development of therapies to serve wounded warriors. He was inducted as a Fellow in the American Association for the Advancement of Science in 2023.